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2.\u6162\u6027\u58d3\u529b\u6703\u52a0\u901f\u8870\u8001\u904e\u7a0b\u3002<\/strong>\u8001\u5e74\u96c4\u6027\u5927\u9f20\u5728\u9577\u671f\u627f\u53d7\u58d3\u529b\u6642\u6703\u7522\u751f\u5931\u63a7\u7684\u7cd6\u76ae\u8cea\u6fc0\u7d20\u3002\u6b63\u5982\u9019\u7bc7Sage\u8ad6\u6587\u4e2d\u6240\u8a0e\u8ad6\u7684\uff0c\u58d3\u529b\u5c0d\u814e\u4e0a\u817a\u76ae\u8cea\u6216\u4e0b\u4e18\u8166-\u5782\u9ad4-\u814e\u4e0a\u817a (HPA) \u8ef8\u6709\u6df1\u9060\u7684\u5f71\u97ff\u3002\u7d55\u80b2\u7684\u72d7\u5152\u7cd6\u76ae\u8cea\u6fc0\u7d20\uff08\u76ae\u8cea\u9187\uff09\u7522\u751f\u5931\u63a7\uff0cHPA\u8ef8\u4e0a\u7684\u58d3\u529b\u6703\u76f4\u63a5\u5c0e\u81f4\u7d55\u80b2\u72d7\u5152\u5011\u5e38\u898b\u5230\u7684\u5167\u5206\u6ccc\u75be\u75c5\uff08\u5373\u5eab\u6b23\u5f0f\u75c7\u3001\u975e\u5178\u578b\u5eab\u6b23\u75c7\u3001\u7532\u72c0\u817a\u4f4e\u4e0b\u3001\u96cc\u6fc0\u7d20\u4ea2\u9032\u75c7\u548c\u7cd6\u5c3f\u75c5\u7b49\uff09\u3002<\/p>\n\n\n\n

\u53e6\u4e00\u9805\u91dd\u5c0d\u8870\u8001\u3001\u58d3\u529b\u548cHPA\u8ef8\u7522\u751f\u7684\u76ae\u8cea\u9187\u904e\u91cf\u7684\u7814\u7a76<\/a>\u8b49\u5be6\u4e86Sage\u8ad6\u6587\u7684\u7406\u8ad6\uff0c\u5373\u6162\u6027\u58d3\u529b\u53ef\u4ee5\u589e\u52a0\u7cd6\u76ae\u8cea\u6fc0\u7d20\u7684\u7522\u751f\uff0c\u5f9e\u800c\u52a0\u901f\u8870\u8001\u8de1\u8c61\u548c\u75c7\u72c0\u7684\u51fa\u73fe\u3002\u7814\u7a76\u7d50\u8ad6\u662f\u300c\u4e86\u89e3\u6b63\u5e38HPA<\/em>\u7684\u8abf\u7bc0\u5f88\u91cd\u8981\uff0c\u56e0\u70ba\u9577\u671f\u589e\u52a0\u7684\u7cd6\u76ae\u8cea\u6fc0\u7d20\u6fc3\u5ea6\u8207X <\/em>\u7d9c\u5408\u75c7\u7684\u4ee3\u8b1d\u7279\u5fb5\uff08\u5167\u81df\u80a5\u80d6\u3001\u80f0\u5cf6\u7d20\u62b5\u6297\u3001\u4f4e\u9ad8\u5bc6\u5ea6\u8102\u86cb\u767d\u6c34\u5e73\u3001\u9ad8\u8840\u58d3\u3001\u4e09\u9178\u7518\u6cb9\u8102\u6c34\u5e73\u5347\u9ad8\uff09\u3001\u8eab\u9ad4\u865b\u5f31\uff08\u6e1b\u5c11\u9aa8\u9abc\u548c\u808c\u8089\u8cea\u91cf\u3001\u6709\u6c27\u80fd\u529b\u4e0b\u964d\uff09\u3001\u514d\u75ab\u6291\u5236\u3001\u6027\u817a\u6a5f\u80fd\u6e1b\u9000\u3001\u751f\u9577\u6fc0\u7d20 (<\/em>GH) <\/em>\u548c\u80f0\u5cf6\u7d20\u6a23\u751f\u9577\u56e0\u5b501\u7f3a\u4e4f\u4ee5\u53ca\u8a18\u61b6\u548c\u7a7a\u9593\u8a8d\u77e5\u53d7\u640d\u6709\u95dc\u3002<\/p>\n\n\n\n

\u7531\u6b64\u53ef\u898b\u72ac\u8c93\u7684\u8377\u723e\u8499\u8ef8\uff08\u5373\u4e0b\u4e18\u8166-\u5782\u9ad4-\u6027\u817a\u548c\/\u6216\u4e0b\u4e18\u8166-\u5782\u9ad4-\u814e\u4e0a\u817a\uff09\u5931\u8abf\uff0c\u53ef\u80fd\u52a0\u901f\u8870\u8001\u904e\u7a0b\uff0c\u5f9e\u800c\u640d\u5bb3\u72ac\u8c93\u7684\u751f\u6d3b\u8cea\u91cf\u548c\u7e2e\u77ed\u4ed6\u5011\u7684\u58fd\u547d\u3002<\/p>\n\n\n\n

\u6700\u5f8c\uff0c\u6b63\u5982\u9019\u4e9b\u7814\u7a76\u8ad6\u6587\u6240\u986f\u793a\u7684\uff0c\u58d3\u529b\u4f3c\u4e4e\u8207\u7d55\u80b2\u9ad8\u5ea6\u76f8\u95dc\u3002\u6027\u985e\u56fa\u9187\uff08\u53d7\u7d55\u80b2\u6216\u5176\u4ed6\u5167\u5206\u6ccc\u5e72\u64fe\u7269\u5f71\u97ff\uff09\u662f\u6c7a\u5b9a\u58d3\u529b\u9069\u61c9\u6027\u76ae\u8cea\u9187\u7522\u751f\u7684\u7a0b\u5ea6\u548c\u6301\u7e8c\u6642\u9593\u7684\u986f\u8457\u751f\u7406\u56e0\u7d20\u3002<\/p>\n\n\n\n

\u6709\u95dc\u72ac\u8c93\u7d55\u80b2\u7d50\u7d2e\u7684\u9032\u4e00\u6b65\u5f71\u97ff\u5065\u5eb7\u53ca\u5f15\u767c\u75be\u75c5\u5c07\u5728\u5176\u4ed6\u6587\u7ae0\u4e2d\u4ecb\u7d39\u3002<\/p>\n\n\n\n

\u5ef6\u4f38\u95b1\u8b80<\/p>\n\n\n\n

\u72ac\u8c93\u7d50\u7d2e\u7684\u7f8e\u9e97\u8207\u54c0\u6101<\/a><\/p>\n\n\n\n

\u53c3\u8003\u8cc7\u6599\uff1a<\/p>\n\n\n\n

https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3791619\/<\/a><\/p>\n\n\n\n

https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2755630\/<\/a><\/p>\n\n\n\n

https:\/\/doi.org\/10.1016\/j.exger.2015.08.008<\/a><\/p>\n\n\n\n

https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3675779\/<\/a><\/p>\n\n\n\n

https:\/\/www.science.org\/doi\/10.1126\/sageke.2002.38.cp21<\/a><\/p>\n\n\n\n

https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3825016\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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